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Chai lab help develop stem cell treatment approach for craniosynostosis | FaceBase

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Chai lab help develop stem cell treatment approach for craniosynostosis

Published 12 January 2021

The Chai laboratory of the Center for Craniofacial Molecular Biology, USC - who have been part of FaceBase from the very beginning - headed a study published in Cell that describes a stem cell-mediated suture regeneration approach that could pave the way to improved treatments for craniosynostosis.

From USC News:

Using stem cells to regenerate parts of the skull, USC scientists partially corrected a skull deformity and reversed learning and memory deficits in young mice with craniosynostosis, a condition estimated to affect 1 in every 2,500 infants born in the United States.

“I started my career as a clinician treating kids with congenital defects, and we always wanted to do something better for these patients,” said study leader Yang Chai, a University Professor and director of the Center for Craniofacial Molecular Biology at the Herman Ostrow School of Dentistry of USC.

“This stem cell-mediated suture regeneration approach truly gives us the hope that one day we can apply this as a biological solution for this biological problem.”

You can read the full article here.